The Application of Network Analysis in Ethnopharmacology

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ChatGPT summary

Unlocking the potential of traditional medicine with Network Pharmacology

This research topic focuses on the use of traditional Chinese medicine to treat various conditions, such as cardiac hypertrophy, diabetic ulcers, pulmonary hypertension, rheumatoid arthritis, and chronic itch. The studies have revealed a variety of potential mechanisms, including inhibiting inflammation, promoting wound healing, regulating estrogen levels, and inhibiting tyrosine kinases.

The studies have found that Chinese patent medicines, such as Erzhi formula, QSYQ, QLQX, KXQW, TXL, DL, SSYX, Wenshenyang recipe, and Wuwei Shexiang pills, can reduce dexamethasone-induced apoptosis, improve synaptic damage, inhibit macrophage M2 polarization, inhibit the PI3K/AKT pathway, inhibit the TLR7/NF-κB signaling pathway, inhibit the abnormal proliferation and migration of pulmonary artery smooth muscle, and inhibit tyrosine kinases. Additionally, compounds such as neferine, liensinine, isoliensinine, and umbelliferone have been identified as potential anti-rheumatic therapeutics.

The studies have also revealed that combining Chinese patent medicines with Western medicine may be more effective than Western medicine alone in treating stable angina, and that Chinese patent medicines may be effective in treating cardiac hypertrophy patients. Additionally, Chinese patent medicines may be effective in treating varicocele-associated male infertility.

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