Diabetic foot is a serious complication of diabetes worldwide. The etiology of diabetic foot is quite complex due to its multifactorial nature. Diabetic neuropathy, peripheral artery disease, foot deformity, high blood glucose and secondary infection all can contribute to diabetic foot ulceration and gangrene, sometimes resulting in minor or major amputations. Several risk factors including old age, long-term diabetes, smoking, foot deformity, and ischemia have been identified in diabetic foot. Many diagnostic methods are used for early-stage diabetic neuropathy and peripheral arterial disease, such as pulse wave, ankle-brachial artery ratio, Sudoscan, gait analysis, etc. Due to the high glucose environment, metabolic disorder, ischemia and peripheral neuropathy, diabetic foot ulcer is much more difficult to heal than common traumatic wounds. Therefore, in addition to existing treatments, new methods or techniques are still needed to improve wound healing. We also expect to find novel pathways to elucidate the complicated mechanisms involved in diabetic foot and diabetic wound healing.
This Research Topic aims to prevent diabetic foot by identifying new risk factors, make an earlier and more precise diagnosis of diabetic foot related complications with new techniques, improve diabetic wound healing through novel pathways, and promote a better understanding of the mechanisms of diabetic foot disease by clinical and fundamental research.
We welcome articles regarding the following sub-topics, including but not limited to:
• Clinical or epidemiological research to investigate new risk factors or risk prediction models for diabetic foot and its related complications, including diabetic peripheral neuropathy and peripheral artery disease;
• Research on new diagnostic techniques using new instruments or innovative use of traditional instruments to detect diabetic foot or related neuropathy and artery diseases;
• Clinical trials or fundamental research to explore novel treatments for diabetic foot, including but not limited to medicine/chemicals, biological material, and physical therapy;
• Clinical trials or fundamental experiments to clarify the underlying molecular and biological mechanisms of diabetic foot to promote a better understanding of diabetic foot and novel therapy in the future.
Diabetic foot is a serious complication of diabetes worldwide. The etiology of diabetic foot is quite complex due to its multifactorial nature. Diabetic neuropathy, peripheral artery disease, foot deformity, high blood glucose and secondary infection all can contribute to diabetic foot ulceration and gangrene, sometimes resulting in minor or major amputations. Several risk factors including old age, long-term diabetes, smoking, foot deformity, and ischemia have been identified in diabetic foot. Many diagnostic methods are used for early-stage diabetic neuropathy and peripheral arterial disease, such as pulse wave, ankle-brachial artery ratio, Sudoscan, gait analysis, etc. Due to the high glucose environment, metabolic disorder, ischemia and peripheral neuropathy, diabetic foot ulcer is much more difficult to heal than common traumatic wounds. Therefore, in addition to existing treatments, new methods or techniques are still needed to improve wound healing. We also expect to find novel pathways to elucidate the complicated mechanisms involved in diabetic foot and diabetic wound healing.
This Research Topic aims to prevent diabetic foot by identifying new risk factors, make an earlier and more precise diagnosis of diabetic foot related complications with new techniques, improve diabetic wound healing through novel pathways, and promote a better understanding of the mechanisms of diabetic foot disease by clinical and fundamental research.
We welcome articles regarding the following sub-topics, including but not limited to:
• Clinical or epidemiological research to investigate new risk factors or risk prediction models for diabetic foot and its related complications, including diabetic peripheral neuropathy and peripheral artery disease;
• Research on new diagnostic techniques using new instruments or innovative use of traditional instruments to detect diabetic foot or related neuropathy and artery diseases;
• Clinical trials or fundamental research to explore novel treatments for diabetic foot, including but not limited to medicine/chemicals, biological material, and physical therapy;
• Clinical trials or fundamental experiments to clarify the underlying molecular and biological mechanisms of diabetic foot to promote a better understanding of diabetic foot and novel therapy in the future.