Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.This Research Topic aims to collect papers on the synthesis and utilization of nitrogen-containing heterocycles, which can provide a versatile entry point to alkaloids and biologically active drugs, pesticides, ligands and catalysts.We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:• Building nitrogen-containing heterocycles.• The transformation from one nitrogen-containing heterocycle to another.• Asymmetric synthesis of molecules bearing a nitrogen-containing heterocycle.• Natural products including alkaloid synthesis.• Nitrogen-containing heterocycles as ligands and catalysts.• Nitrogen-containing drugs and pesticides.
Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.This Research Topic aims to collect papers on the synthesis and utilization of nitrogen-containing heterocycles, which can provide a versatile entry point to alkaloids and biologically active drugs, pesticides, ligands and catalysts.We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:• Building nitrogen-containing heterocycles.• The transformation from one nitrogen-containing heterocycle to another.• Asymmetric synthesis of molecules bearing a nitrogen-containing heterocycle.• Natural products including alkaloid synthesis.• Nitrogen-containing heterocycles as ligands and catalysts.• Nitrogen-containing drugs and pesticides.