The latest WHO classification of endocrine and neuroendocrine tumors has encompassed a highly heterogeneous group of neoplasms that arise from (neuro)endocrine cells from endocrine glands or the diffuse neuroendocrine system throughout the body. These neoplasms display a wide spectrum of clinical behaviors, ranging from indolent lesions to aggressive and metastatic diseases. Currently, the treatment modalities of endocrine and neuroendocrine tumors mainly depend on histological diagnosis and staging, which vary across anatomic locations. In the era of individualized therapy, a deeper insight into the heterogenous pathology and genetic alterations of endocrine and neuroendocrine tumors is mandatory to facilitate more precise treatment strategies and risk stratification.
This Research Topic aims to create a forum for recent advances in the pathology and genetics of endocrine and neuroendocrine tumors, which we hope to translate into clinical implications for diagnosis and therapy.
We welcome submissions of the following subtopics, but not limited to:
- Pathological diagnosis and differential diagnosis of endocrine and neuroendocrine tumors;
- Molecular classification of endocrine and neuroendocrine tumors;
- Identification and validation of clinically relevant biomarkers of endocrine and neuroendocrine tumors;
- Characterization of hereditary syndromes associated with endocrine and neuroendocrine tumors.
The latest WHO classification of endocrine and neuroendocrine tumors has encompassed a highly heterogeneous group of neoplasms that arise from (neuro)endocrine cells from endocrine glands or the diffuse neuroendocrine system throughout the body. These neoplasms display a wide spectrum of clinical behaviors, ranging from indolent lesions to aggressive and metastatic diseases. Currently, the treatment modalities of endocrine and neuroendocrine tumors mainly depend on histological diagnosis and staging, which vary across anatomic locations. In the era of individualized therapy, a deeper insight into the heterogenous pathology and genetic alterations of endocrine and neuroendocrine tumors is mandatory to facilitate more precise treatment strategies and risk stratification.
This Research Topic aims to create a forum for recent advances in the pathology and genetics of endocrine and neuroendocrine tumors, which we hope to translate into clinical implications for diagnosis and therapy.
We welcome submissions of the following subtopics, but not limited to:
- Pathological diagnosis and differential diagnosis of endocrine and neuroendocrine tumors;
- Molecular classification of endocrine and neuroendocrine tumors;
- Identification and validation of clinically relevant biomarkers of endocrine and neuroendocrine tumors;
- Characterization of hereditary syndromes associated with endocrine and neuroendocrine tumors.