The SARS-CoV-2 virus has led to the worldwide outbreak of the twentieth century. Current knowledge on SARS-CoV-2 acute infection has dramatically increased. Three years after the main outbreak, the presence of long-lasting symptoms after the acute infection called long COVID or post-COVID-19 syndrome, affects millions of individuals worldwide. Increasing literature supports the presence of more than 100 potential symptoms after the acute phase of infection such as:· extreme fatigue, dizziness, and insomnia· depression and anxiety, memory and concentration impairments· loss of smell or taste, tinnitus, and earaches· chest pain, heart palpitations, tightness, muscle aches.However, several gaps still are present in the identification, timeframe, mechanisms, and treatment strategies for the management of long-COVID.This Research Topic aims to update the current understanding of long COVID in relation to the underlying mechanisms, classification, and potential treatment approaches. Identification of groups of individuals with long-COVID according to mechanisms or clinical symptomatology could lead to better treatment approaches.We are pleased to invite you to this Research Topic “Updating Long COVID: Mechanisms, Risk Factors, and Treatment”. This Research Topic will focus on all these aspects of post-COVID-19 condition, a topic of emerging relevance due to the absence of an effective treatment. This is highly relevant since long-COVID is independent of the SARS-CoV-2 variant or the implementation of vaccination programs. We invite researchers/clinicians to submit original articles, systematic reviews, narrative reviews, meta-analyses, cohort and case-control studies related to identification or management of post-COVID subgroups to this Research Topic.
The SARS-CoV-2 virus has led to the worldwide outbreak of the twentieth century. Current knowledge on SARS-CoV-2 acute infection has dramatically increased. Three years after the main outbreak, the presence of long-lasting symptoms after the acute infection called long COVID or post-COVID-19 syndrome, affects millions of individuals worldwide. Increasing literature supports the presence of more than 100 potential symptoms after the acute phase of infection such as:· extreme fatigue, dizziness, and insomnia· depression and anxiety, memory and concentration impairments· loss of smell or taste, tinnitus, and earaches· chest pain, heart palpitations, tightness, muscle aches.However, several gaps still are present in the identification, timeframe, mechanisms, and treatment strategies for the management of long-COVID.This Research Topic aims to update the current understanding of long COVID in relation to the underlying mechanisms, classification, and potential treatment approaches. Identification of groups of individuals with long-COVID according to mechanisms or clinical symptomatology could lead to better treatment approaches.We are pleased to invite you to this Research Topic “Updating Long COVID: Mechanisms, Risk Factors, and Treatment”. This Research Topic will focus on all these aspects of post-COVID-19 condition, a topic of emerging relevance due to the absence of an effective treatment. This is highly relevant since long-COVID is independent of the SARS-CoV-2 variant or the implementation of vaccination programs. We invite researchers/clinicians to submit original articles, systematic reviews, narrative reviews, meta-analyses, cohort and case-control studies related to identification or management of post-COVID subgroups to this Research Topic.